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Studies on the Mechanism involved in Negative Temperature Coefficient of Toxicity of Pyrethrum
| Title: | Studies on the Mechanism involved in Negative Temperature Coefficient of Toxicity of Pyrethrum | | Authors: | Z. Osmani and M.B Naidu | | Publication: | Indian Journal of Entomology / The Entomological Society of India | | Enumeration: | Vol 32, June 1970, part 2 | | Abstract: | The Mechanism involved in negative temperature coefficient of toxicity of pyrethrum has been studied using isolated cockroach heart technique.
Pyrethrum at lower concentrations causes temporary increase in the heartbeat frequency, while at higher concentrations a sudden depression. The depressant phase of action increases at higher temperature thereby showing increased action. But at low temperature no significant change was seen. On the contrary, blood extracted from cockroaches maintained at 35 C produce temporary increase in the heart beat frequency, while blood extracted from cockroaches maintained at 15 C causes a rapid decline, thus showing toxic action. It is inferred from these results that some substance is released by the action of pyrethrum which plays an important role in producing toxicity at low temperature, while it does not do so at higher temperature.
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